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Down Syndrome as an indicator for pediatric otolaryngologic procedures
Terral A Patel1, Shaun A Nguyen1, David R White1
1Department of Otolaryngology - Head and Neck Surgery, 135Rutledge Avenue, MSC 550, Charleston, SC, 29425, USA.
International Journal of Pediatric Otorhinolaryngology
|July 30, 2018
Summary
Patients with Down syndrome (DS) undergo specific otolaryngologic procedures more frequently than others. This study analyzed national data to understand these differences in ENT procedures for DS patients.
Area of Science:
- Otolaryngology
- Genetics
- Pediatric Surgery
Background:
- Down syndrome (DS) is the most common human chromosome abnormality.
- The unique phenotype of DS necessitates various otolaryngologic surgical interventions.
- Understanding procedure patterns in DS is crucial for specialized care.
Purpose of the Study:
- To analyze national data on otolaryngologic procedures in patients with Down syndrome.
- To identify specific ENT procedures over-represented or under-represented in the DS population.
- To compare risk profiles associated with these procedures in DS patients.
Main Methods:
- Utilized the 2012-2015 American College of Surgeons' National Surgical Quality Improvement Program-Pediatric database.
- Identified DS patients using ICD-9 code 758.0 and ENT procedures via CPT codes.
- Grouped procedures into 18 categories and analyzed frequency, outcomes, and risk profiles.
Main Results:
- DS patients showed significant over-representation in tracheostomy, endoscopy, laryngoscopy, tracheoplasty, myringoplasty, and tympanoplasty procedures.
- DS patients were significantly under-represented in procedures for abscess, palatoplasty, congenital neck cyst excision, and cochlear implantation.
- Logistic regression confirmed these over- and under-representation patterns; no significant differences in outcomes were found.
Conclusions:
- Down syndrome appears to predispose patients to require certain otolaryngologic procedures more than others.
- Specific ENT surgical patterns exist within the DS population.
- Further research may elucidate the underlying reasons for these procedural disparities.
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