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Source and Route of Pyrrolizidine Alkaloid Contamination in Tea Samples
Published on: September 28, 2022
Piperidine alkaloids and xanthone from the roots of Caulophyllum robustum Maxim
Hui-Xiang Yang1, Wei Li1, Qian Li1
1School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China.
Abstract:
Two undescribed piperidine racemates, (±)-caulophines A and B (1 and 2), a new N-containing xanthone derivative (3), together with six known piperidines, were isolated from the roots of Caulophyllum robustum Maxim. Their structures were determined by extensive spectroscopic techniques. Compounds 3 and 7 exhibited weak cytotoxicities against human palace cancer hela cell line with inhibitory rates of 32.2% and 39.7%, respectively, at the concentration of 40 μM.
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