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Updated: Feb 7, 2026

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome
Published on: March 31, 2023
The role of the gut microbiome during host ageing
Jens Seidel1, Dario Riccardo Valenzano1,2
1Max Planck Institute for Biology of Ageing, Cologne, Germany.
Abstract:
Gut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play a causal role in host ageing and life span has remained an open question for a long time. Recent work in model organisms has revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.
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