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Updated: Feb 7, 2026
09:41
An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
9.1K
Unusual Presentation of Multiple Myeloma
Jeong Suk Jeon1, Sang Yeoup Lee2, Eun Jeong Choi3
1Health promotion center, Bongseng Memorial Hospital, Busan, South Korea
JNMA; Journal of the Nepal Medical Association
|July 31, 2018
Summary
Malignancy is a risk factor for venous thromboembolism (VTE). This case highlights how multiple myeloma can present initially as unprovoked VTE, emphasizing the need for thorough investigation.
Area of Science:
- Hematology
- Oncology
- Internal Medicine
Background:
- Malignancy is a known risk factor for venous thromboembolism (VTE).
- Determining if an underlying cancer causes unprovoked VTE can be challenging.
- Idiopathic VTE affects approximately 25% of patients.
Observation:
- A 63-year-old woman with a history of unprovoked VTE presented with persistent cough and dyspnea.
- Her symptoms had been ongoing for six months prior to diagnosis.
- The patient had a prior unprovoked VTE event 10 months earlier.
Findings:
- The patient was ultimately diagnosed with multiple myeloma.
- This diagnosis was made after a period of investigating her recurrent respiratory symptoms.
Implications:
- This case underscores the potential link between multiple myeloma and unprovoked venous thromboembolism.
- It highlights the importance of considering hematologic malignancies in patients with idiopathic VTE.
- Further research may elucidate the mechanisms connecting multiple myeloma and VTE risk.
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