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Updated: Feb 7, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
[Molar incisor hypomineralization]
Joëlle A. Dulla1, Markus Schaffner1, Adrian Lussi1
1Klinik für Zahnerhaltung, Präventiv- und Kinderzahnmedizin, Zahnmedizinische Kliniken der Universität Bern
Abstract:
Molar incisor hypomineralization (MIH) describes a developmental enamel formation disorder caused by defective calcium and phosphate deposition by the ameloblasts during enamel matrix formation and enamel maturation. The first permanent molars are affected. The first permanent incisors may or may not be affected (Fig. 1, 2). The prevalence is 10 to 19%. The etiology of MIH is still unknown.
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