Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Proteins in the Human Body01:28

Role of Proteins in the Human Body

6.4K
Proteins are the building block of life. They are also  the most abundant macromolecules with as many diverse roles in the body. They are part of many structural components that provide unique shapes and structures to animal cells, tissues, and organs. In addition, they also act as biological catalysts and carry out several anabolic and catabolic reactions. Notably, some proteins are chemical messengers and regulate many critical processes, such as metabolism, growth, and development. They...
6.4K
Structural Organization of the Human Body: An Overview01:18

Structural Organization of the Human Body: An Overview

29.5K
It is convenient to consider the body's structures in terms of fundamental levels of organization that increase in complexity: subatomic particles, atoms, molecules, organelles, cells, tissues, organs, organ systems, and organisms.
To study the chemical level of organization, scientists consider the simplest building blocks of matter: subatomic particles, atoms, and molecules. All matter in the universe is composed of one or more unique pure substances called elements, familiar examples of...
29.5K
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

6.5K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
6.5K
Body Temperature01:25

Body Temperature

4.8K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
4.8K
Body Temperature01:07

Body Temperature

1.5K
Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
1.5K
Centroid of a Body01:16

Centroid of a Body

1.9K
The centroid is an important concept in engineering, physics, and mechanics. It is the geometric center of a body. It always lies within the body except in cases with holes or cavities. When the material that a body is composed of is uniform or homogeneous, the centroid coincides with its center of mass or the center of gravity.
For a homogeneous body with constant density, the centroid can usually be found using equations representing a balance of the moments of the body's volume. If the...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Gene regulation in lymphocyte development and response.

Frontiers in immunology·2026
Same author

Morphomechanic tuning of ERK by actin-TFII-IΔ regulates cell identity.

bioRxiv : the preprint server for biology·2026
Same author

Transcription factor TFII-I fine tunes innate properties of B lymphocytes.

Frontiers in immunology·2023
Same author

Elucidating the structure and function of the nucleus-The NIH Common Fund 4D Nucleome program.

Molecular cell·2023
Same author

Validation of antibodies: Lessons learned from the Common Fund Protein Capture Reagents Program.

Science advances·2021
Same author

Role of the multifunctional transcription factor TFII-I in DNA damage repair.

DNA repair·2021

Related Experiment Video

Updated: Feb 7, 2026

AFM-based Mapping of the Elastic Properties of Cell Walls: at Tissue, Cellular, and Subcellular Resolutions
10:26

AFM-based Mapping of the Elastic Properties of Cell Walls: at Tissue, Cellular, and Subcellular Resolutions

Published on: July 24, 2014

13.5K

Toward mapping the human body at a cellular resolution.

Ananda L Roy1, Richard S Conroy1

  • 1Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD 20892.

Molecular Biology of the Cell
|July 31, 2018
PubMed
Summary
This summary is machine-generated.

Mapping the human body at the cellular level presents significant challenges and opportunities. International collaboration is key to comprehensively charting molecular characteristics of trillions of human cells.

More Related Videos

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
13:49

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging

Published on: January 11, 2011

35.1K
High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

13.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

AFM-based Mapping of the Elastic Properties of Cell Walls: at Tissue, Cellular, and Subcellular Resolutions
10:26

AFM-based Mapping of the Elastic Properties of Cell Walls: at Tissue, Cellular, and Subcellular Resolutions

Published on: July 24, 2014

13.5K
High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
13:49

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging

Published on: January 11, 2011

35.1K
High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

13.5K

Area of Science:

  • Human biology
  • Molecular biology
  • Cellular mapping

Background:

  • The adult human body contains approximately 37 trillion cells.
  • Each cell possesses potentially unique molecular characteristics.
  • Understanding cellular heterogeneity is crucial for human biology.

Purpose of the Study:

  • To describe challenges and opportunities in mapping cellular molecular characteristics.
  • To highlight areas for international collaboration.
  • To advance comprehensive human body mapping at cellular resolution.

Main Methods:

  • This perspective discusses existing and emerging techniques for cellular characterization.
  • It reviews data integration strategies for large-scale molecular mapping.
  • It emphasizes the need for standardized protocols in single-cell analysis.

Main Results:

  • Mapping cellular molecular profiles across the human body is complex.
  • Significant technological and logistical hurdles exist.
  • Opportunities for international cooperation are substantial.

Conclusions:

  • Comprehensive cellular-level mapping of the human body is an ambitious but achievable goal.
  • International collaboration is essential for success.
  • Such mapping will revolutionize precision medicine and biological understanding.