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Updated: Feb 7, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Dinuclear tethered pyridine, diimine complexes
Wiebke Dammann1, Tabea Buban, Carl Schiller
1Institut für Anorganische und Angewandte Chemie, Fachbereich Chemie, Universität Hamburg, Martin Luther King Platz 6, 20146 Hamburg, Germany. burger@chemie.uni-hamburg.de.
Abstract:
The regioselective borylation of pyridine precursors, followed by Suzuki coupling with dihalogenated linker molecules, provides access to tethered ligands. Complexation with MX2 salts results in the formation of dinuclear metal compounds. Syntheses and crystal structures are reported along with a discussion on the rigidity/flexibility of these new ligand systems.
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