Related Experiment Video

Updated: Feb 7, 2026

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
08:10

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis

Published on: December 14, 2019

11.7K

Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis

Aliye Uc, M Bridget Zimmerman1, Michael Wilschanski2

  • 1Department of Biostatistics, University of Iowa, Iowa City, IA.

Pancreas
|July 31, 2018
PubMed

Insights

Obesity in children may delay the first episode of acute pancreatitis and diagnosis of chronic pancreatitis (CP). Further research is needed to understand obesity's full impact on pediatric CP progression and severity.

Area of Science:

  • Pediatric Gastroenterology
  • Metabolic Disorders
  • Pancreatic Diseases

Background:

  • Pediatric pancreatitis is a significant health concern.
  • The role of obesity in the development and progression of pediatric pancreatitis requires further investigation.

Purpose of the Study:

  • To evaluate the influence of obesity on pediatric acute recurrent pancreatitis and chronic pancreatitis (CP).

Main Methods:

  • Utilized the INSPPIRE cohort data, assessing body mass index (BMI) using CDC criteria.
  • Employed Cochran-Armitage and Jonckheere-Terpstra tests to analyze trends and associations.

Main Results:

  • Obesity was associated with a later age of first acute pancreatitis episode and CP diagnosis.
  • Obese children showed a lower likelihood of CP and a higher likelihood of acute inflammation on imaging.
  • Hypertriglyceridemia was more prevalent in overweight or obese children.

Conclusions:

  • Overweight and obesity appear to delay the onset of acute pancreatitis and CP diagnosis in children.
  • The long-term effects of obesity on pediatric chronic pancreatitis severity and progression warrant additional research.
Abstract

More Related Videos

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.7K
Acute and Chronic Models of Hyperglycemia in Zebrafish: A Method to Assess the Impact of Hyperglycemia on Neurogenesis and the Biodistribution of Radiolabeled Molecules13:35

Acute and Chronic Models of Hyperglycemia in Zebrafish: A Method to Assess the Impact of Hyperglycemia on Neurogenesis and the Biodistribution of Radiolabeled Molecules

Published on: June 26, 2017

13.9K

Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.3K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
745
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
373
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
878
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.4K
Impact of Groups on Groups01:19

Impact of Groups on Groups

Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
251