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Related Experiment Video

Updated: Feb 7, 2026

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
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Dark adaptation changes in highly myopic patients.

Arnaud Messerlin1, Mathieu Greth1, Tristan Bourcier1

  • 1Department of Ophthalmology, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France.

European Journal of Ophthalmology
|August 1, 2018
PubMed
Summary

Dark adaptation time did not differ between highly myopic and emmetropic patients. However, longer axial length in myopia correlated with increased dark adaptation time, especially with retinal lesions.

Keywords:
Axial lengthdark adaptationhigh myopiaretinal pigment epithelium atrophy

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Area of Science:

  • Ophthalmology
  • Retinal Physiology

Background:

  • High myopia is associated with structural changes in the eye.
  • Dark adaptation is crucial for vision in low light conditions.

Purpose of the Study:

  • To compare dark adaptation time between highly myopic and emmetropic individuals.
  • To investigate the correlation between axial length and dark adaptation in myopia.
  • To assess the impact of retinal lesions on dark adaptation in myopia.

Main Methods:

  • Retrospective study including 25 highly myopic patients (≥-6.00 D) and 25 matched emmetropic controls.
  • Automated adaptometry used to measure rod intercept, reflecting rod-mediated dark adaptation.
  • Axial length measurement and fundus photography for retinal atrophy detection.

Main Results:

  • No significant difference in mean dark adaptation time between myopic and control groups (p=0.79).
  • Significant positive correlation found between axial length and dark adaptation time in highly myopic patients (p=0.0003).
  • Dark adaptation was significantly prolonged in myopic patients with retinal pigment epithelium atrophy (p=0.0398).

Conclusions:

  • Dark adaptation time is not significantly different between highly myopic and emmetropic eyes.
  • Axial length is a significant predictor of prolonged dark adaptation in severe myopia.
  • Retinal pigment epithelium atrophy exacerbates impaired dark adaptation in myopic individuals.