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Updated: Aug 11, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
[Dynamic CT of lymphoma manifestations of the liver and spleen]
Abstract:
Fourteen patients with lymphoma involving the liver and/or spleen were examined by dynamic CT. Lymphoma lesions show little enhancement with respect to the spleen and usually also when compared with liver tissue. On two occasions there was a definite increase in density during the arterial phase and dynamic CT could not distinguish the lesions from tumours of hepatic origin. One circumscribed lymphomatous lesion of the liver and six splenic infiltrates were only visible during the first few seconds after a bolus of contrast material had been injected. Dynamic CT does not usually differentiate diffuse involvement of the liver and spleen. In this situation, lack of a trabecular structure of the spleen during the arterial phase and a low peak of the time-density curve may suggest diffuse infiltration.
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