[Peripheral neuropathies associated with monoclonal gammapathies. Value of electrophysiologic studies]

An electrophysiological study was performed in 19 patients with polyneuropathy associated with a monoclonal gammopathy. This study has shown some difference according to the type of the gammopathy and the benign or malignant nature of the disease. Patients with benign IgM gammopathy are in an homogenous group. In every case the neuropathy is of the demyelinating type. In the other groups, the neuropathy is less homogenous. Most of the time it was predominantly of axonal type. Within the myeloma group, the neuropathy is more severe and the denervation pattern is marked.