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An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 28, 2010
Computed tomography imaging features of benign ovarian Brenner tumors
Yuying Zhao1, Xinfeng Mao1, Lidi Yao1
1Department of Radiology, Huzhou Central Hospital, Huzhou, Zhejiang 313003, P.R. China.
Abstract:
The present study aimed to describe the computed tomography (CT) imaging features of ovarian Brenner tumor for diagnostic accuracy and disease understanding. The CT imaging features of 9 cases of ovarian Brenner tumor confirmed by surgery and pathology were retrospectively analyzed and compared. Of the 9 cases of ovarian Brenner tumor, 3 were right located and 6 were left located with clear borders; 7 with round or oval shapes, while 2 were with irregular and lobulated morphology; 5 solid lesions presented with multiple scattered calcification shadows inside with moderate enhancement, while 3 cystic lesions were presented with mixed solid and cystic composition, and significant enhancement was identified in the solid component, but not in the cystic component. Furthermore, papillary projections inside and mild nodular enhancement were observed in one case of cystic lesion. The pathological analysis demonstrated that an epithelium nest composed the tumors with urothelial like cells and fibrous matrix. Of the 9 cases, 5 epithelial nests exhibited adeno-like cystic lumen without cell mitosis phase. All cases were diagnosed with benign ovarian Brenner tumor. Specific CT imaging features of ovarian Brenner tumor can be identified and pathological examinations are required for diagnosis confirmation.
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