Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy
Daiki Uchida1, Ayataka Fujimoto1, Tomohiro Yamazoe1
1Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Shizuoka, Japan.
Abstract:
A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial. We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired awareness seizures and behavior arrest. Seizures were uncontrolled despite 3 years of pharmacotherapy, but suddenly stopped after shunt removal. Our case supports the hypothesis that drug-resistant epilepsy can be influenced by changes in ICP. In particular, this case indicates that elevations in ICP may help reduce some seizures.
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