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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Otogenic brain abscesses: A systematic review.

Maria J Duarte1,2, Elliott D Kozin1,2, Miriam B Barshak2,3,4

  • 1Department of Otolaryngology, Harvard Medical School Boston Massachusetts U.S.A.

Laryngoscope Investigative Otolaryngology
|August 1, 2018
PubMed
Summary
This summary is machine-generated.

Otogenic brain abscesses, a rare complication of ear infections, demand high suspicion for diagnosis. This review analyzes 1307 cases, detailing symptoms, common bacteria like Proteus mirabilis, and treatment outcomes.

Keywords:
Brain abscesscomputed tomographymagnetic resonance imagingotologic infection

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Infectious Diseases

Background:

  • Otogenic brain abscesses are severe, life-threatening complications of otologic infections.
  • Their low prevalence necessitates a high index of suspicion for timely diagnosis.

Purpose of the Study:

  • To systematically review otogenic brain abscesses.
  • To analyze clinical presentation, bacteriology, location, treatment, morbidity, and mortality.

Main Methods:

  • Systematic literature review following PRISMA guidelines.
  • Searched PubMed, Cochrane CENTRAL, Google Scholar, and Scopus.
  • Included 29 studies with 1307 otogenic abscess cases.

Main Results:

  • Abscesses predominantly in the temporal lobe (55%) and cerebellum (28%).
  • Most patients had chronic suppurative otitis media (88.3%). Common symptoms: headache, altered mental status, papilledema.
  • Proteus mirabilis was the most common pathogen; burr hole aspiration was a frequent treatment. Mortality was 8.11% post-CT.

Conclusions:

  • Otogenic brain abscesses, though rare, are serious complications of otitis media.
  • High index of suspicion, advanced imaging, and multidisciplinary care are vital for diagnosis and management.