Related Experiment Video

Updated: Feb 7, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
09:17

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Published on: July 29, 2011

15.3K

Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial

Vesna Nikolova-Krstevski1,2, Soeren Wagner3, Ze Yan Yu2,4

  • 1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.

JACC. Basic to Translational Science
|August 1, 2018
PubMed

Keywords:
AE, atrial endocardiumAF, atrial fibrillationAPB, aminoethoxydiphenyl borateAb, antibodyCM, cardiomyocyteCa2+, calciumDil-Ac-LDL, dil acetylated−low-density lipoproteinET, endothelinHUVEC, human umbilical vein endothelial cellOAG, 1-oleoyl-2-acetyl-sn-glycerolTAC, thoracic aortic constrictionTRPC, transient receptor potential channelTet, tetanus toxin[Ca2+]i, intracellular global Ca2+atrial endocardiumendotheliumiPS, induced pluripotent stemmechanical stretchtransient receptor potential channels

More Related Videos

Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo09:38

Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo

Published on: February 20, 2018

6.9K
Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

19.6K

Related Concept Videos

Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.0K
Crossing Over01:34

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
172.1K
Crossing Over01:30

Crossing Over

Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
6.5K
Monohybrid Crosses01:20

Monohybrid Crosses

Overview
239.6K
Cross-Sectional Research01:50

Cross-Sectional Research

In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.7K
Ion Channels01:19

Ion Channels

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.5K