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Updated: Feb 7, 2026

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
Published on: January 20, 2022
Action and Ion Mobility Spectroscopy of a Shortened Retinal Derivative
Lihi Musbat1, Shirrel Assis1, Jonathan M Dilger2
1Department of Physics and Institute of Nanotechnology, Bar-Ilan University, 5290002, Ramat-Gan, Israel.
Abstract:
The development of tandem ion mobility spectroscopy (IMS) known as IMS-IMS has led to extensive research into isomerizations of isolated molecules. Many recent works have focused on the retinal chromophore which is the optical switch used in animal vision. Here, we study a shortened derivative of the chromophore, which exhibits a rich IM spectrum allowing for a detailed analysis of its isomerization pathways, and show that the longer the chromophore is, the lower the barrier energies for isomerization are. Graphical Abstract.
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