Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adaptability of Cytoskeletal Filaments01:12

Adaptability of Cytoskeletal Filaments

6.0K
The cytoskeleton is a complex dynamic structure performing varied functions based on cellular requirements. The adaptability of the individual filaments in the cytoskeleton determines their ability to perform various functions within the cell. It can undergo rapid reorganization during processes like cell division or remain stable for several hours as in the interphase. The adaptability of these filaments depends on stringent regulatory mechanisms. The microfilament and microtubules of the...
6.0K
Natural Selection and Adaptation01:15

Natural Selection and Adaptation

1.4K
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
1.4K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

9.7K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
9.7K
Stimulants01:29

Stimulants

1.0K
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
1.0K
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

7.1K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
7.1K
Adaptations that Reduce Water Loss01:57

Adaptations that Reduce Water Loss

28.2K
Though evaporation from plant leaves drives transpiration, it also results in loss of water. Because water is critical for photosynthetic reactions and other cellular processes, evolutionary pressures on plants in different environments have driven the acquisition of adaptations that reduce water loss.
28.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced broad-band intermuscular coherence in myoclonus: a targeted characterization study.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Hand-Specific Engagement of Cerebello-Thalamo-Cortical and Higher-Order Sensorimotor Networks in Essential Tremor: Converging Evidence From GLM and MVPA-Based fMRI Analysis.

European journal of neurology·2026
Same author

Machine learning based EMG analysis of intermuscular coherence and cumulant density in tremor and myoclonus.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Discrepancies between patient-reported and physician-reported severity and disability in functional and non-functional movement disorders.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

An 18-fluorodeoxyglucose-PET study in <i>SGCE</i> positive and negative myoclonus-dystonia.

Brain communications·2026
Same author

Future directions in the treatment of brain metastases: evaluating the role of cellular players in the tumour microenvironment.

Acta neuropathologica·2026

Related Experiment Video

Updated: Feb 7, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

23.1K

Toward adaptive deep brain stimulation for dystonia.

Dan Piña-Fuentes1,2, Martijn Beudel2,3, Simon Little4

  • 1Departments of1Neurosurgery and.

Neurosurgical Focus
|August 2, 2018
PubMed
Summary

Abnormal neural oscillations in the cortico-basal ganglia-thalamo-cortical network are key to movement disorders. This review explores using these oscillations as biomarkers for adaptive deep brain stimulation (aDBS) in dystonia.

Keywords:
AA = agonist-antagonistCBGTC = cortico-basal ganglia-thalamo-corticalECoG = electrocorticographyEEG = electroencephalographyEMG = electromyographyGPi = internal globus pallidusLFP = local field potentialPD = Parkinson’s diseaseaDBS = adaptive deep brain stimulationadaptive deep brain stimulationcDBS = continuous DBSdystoniaelectromyographylocal field potentialslow-frequency oscillations

More Related Videos

Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring
06:32

Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring

Published on: July 14, 2023

1.9K
Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

23.1K
Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring
06:32

Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring

Published on: July 14, 2023

1.9K
Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.5K

Area of Science:

  • Neuroscience
  • Neurology
  • Biomarkers

Background:

  • Abnormal neural oscillations in the cortico-basal ganglia-thalamo-cortical (CBGTC) network are implicated in movement disorder pathophysiology.
  • These oscillations hold potential as biomarkers for therapeutic interventions.
  • Adaptive deep brain stimulation (aDBS) utilizes pathological oscillations as feedback signals.

Purpose of the Study:

  • To review current research on pathological oscillations in dystonia.
  • To identify potential biomarkers for adaptive deep brain stimulation (aDBS) in dystonia patients.

Main Methods:

  • Literature review of scientific research on neural oscillations in dystonia.
  • Analysis of potential biomarkers for aDBS.

Main Results:

  • Pathological oscillations are a significant factor in dystonia.
  • Specific oscillation characteristics may serve as biomarkers for aDBS.

Conclusions:

  • Understanding pathological oscillations in dystonia is crucial for developing effective aDBS.
  • Biomarkers derived from neural oscillations could personalize aDBS therapy for dystonia.