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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Papular elastorrhexis: a rare and benign disease
Layla Comel Corso Perito de Bem1, Alessandra Coppini2, Vanessa Vinderfeltes Padilha1
1Dermatology Service, Hospital Universitário Evangélico de Curitiba, Faculdade Evangélica do Paraná, Curitiba (PR), Brazil.
Abstract:
Papular elastorrhexis is an acquired disease of elastic tissue; considered rare, its etiology and pathogenesis remain unknown. The vast majority of cases occur in women in the first or second decade of life. The disease manifests as multiple uniformly-sized, circumscribed, hypochromic and achromic papules located predominantly on the trunk and upper extremities. The lesions are generally asymptomatic and have a stable evolution over years. Its diagnosis is based on clinical and histopathological findings. The benignity of papular elastorrhexis and the subtlety of its clinical changes make the expectant treatment perfectly viable. The authors present one case in a young female patient.
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