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Updated: Feb 7, 2026

Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy
Published on: November 29, 2017
Reflectance confocal microscopy as a tool for screening surgical margins of basal cell carcinoma
Danilo Augusto Teixeira1,2, Gisele Gargantini Rezze3, Maria Aparecida Silva Pinhal4
1Graduate Master's Program in Health Sciences, Faculdade de Medicina do ABC, Santo André (SP), Brazil.
Abstract:
Surgical excision of basal cell carcinoma with minimum margins requires serial assessment of layers by frozen histopathology in the case of Mohs micrographic surgery. Evaluation of presurgical tumor margins by in vivo reflectance confocal microscopy is a potential alternative. We selected 12 basal cell carcinoma lesions that were analyzed by confocal microscopy to define margins. The lesions were excised by Mohs surgery. Six tumors showed negative margins in the first phase of Mohs micrographic surgery. We concluded that reflectance confocal microscopy can be useful in the preoperative definition of basal cell carcinoma margins.
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