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Updated: Feb 7, 2026

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
Published on: November 8, 2019
[Clinical study of five combined operation for anus reconstruction]
Objective:
To study the effect of five combined operation for anus reconstruction after Miles operation in patients with lower colorectal cancer.
Methods:
60 patients with lower colorectal cancers received Miles operation, followed by five combined operation for anus reconstruction (internal and external anal sphincter, rectal flap, rectal angle, anus perineal reconstruction).
Results:
5-6 days after operation, all cases had desire to excretion.2-3 weeks lateral, all cases desired to control excretion and excreted 1 or 2 times per-day. Internal rectum testing showed the static pressure in anus, the constrictive pressure, and the static pressure in rectum were all normal. The survival rate of patients over 5 years was beyond 88%.
Conclusions:
It suggests that five combined operation for anus reconstruction after Miles operation could avoid man-made anus on abdomen. It can improve the patients' life quality, long-term survival rate. And it's also economical method for patients.
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