[Synthetic Ca++-dependent proton carrier]

N V Lukoianov, O A Raevskiĭ, A S Shtepanek

|January 1, 1986

Abstract:

Influence of 1,5-(3,3'-dimethylphosphate)diphenoxy-3-oxapentane (DDOP) on conductivity (G) of bilayers of common fabbit brain lipids is studied. It has been found that DDOP increases the bilayer conductivity in the presence of Ca++ and Mg++ (G-maximum at pH = 7.0) they do not act in the presence of K+, Na+. pK'DDOP, pK"DDOP values are equal to 1.2, and 7.7 respectively as determined by titration. Formation of "pseudomacrocyclic" DDOP structure is suggested. The role of Ca++, Mg++ ions seems to consist in lipophilisation of ionized forms of DDOP.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

[Computer modeling of blood brain barrier permeability of physiologically active compounds].

Biomeditsinskaia khimiia·2014

[Linear and nonlinear QSAR models of acute intravenous toxicity to mice for organic chemicals].

Biomeditsinskaia khimiia·2013

[Acute intravenous toxicity to mice calculations on the basis local regression models in superoverlapping clusters (LRMSC)].

Biomeditsinskaia khimiia·2013

[Computer classification models on the relationship between chemical structures of compounds and drugs with their blood brain barrier penetration].

Biomeditsinskaia khimiia·2012

[Molecular modeling of acetylcholinesterase interaction with irreversible and reversible organophosphorous inhibitors].

Biomeditsinskaia khimiia·2011

[Quantitative dependence of structure-antiseizure activity in a series of macrocyclic compounds].

Voprosy meditsinskoi khimii·1998

See all related articles

Related Experiment Videos

[Synthetic Ca++-dependent proton carrier]

Related Concept Videos

[Computer modeling of blood brain barrier permeability of physiologically active compounds].

[Linear and nonlinear QSAR models of acute intravenous toxicity to mice for organic chemicals].

[Acute intravenous toxicity to mice calculations on the basis local regression models in superoverlapping clusters (LRMSC)].

[Computer classification models on the relationship between chemical structures of compounds and drugs with their blood brain barrier penetration].

[Molecular modeling of acetylcholinesterase interaction with irreversible and reversible organophosphorous inhibitors].

[Quantitative dependence of structure-antiseizure activity in a series of macrocyclic compounds].

[On Atomic Nuclear Fusion Processes at Low-Temperatures. An Enhancement of the Probability of Transition through a Potential Barrier Due to the So-Called Barrier Anti-Zeno Effect].

[An Iterative Continuous-Event Model of the Population Outbreak of Phytophagous Hemiptera].

[Providing the Optimal Insolation of a Photobiological Architectural Shell for Microalgae Cultivation].

[Neurodynamic Bases of Imitation Learning and Episodic Memory].

[Some Approaches to Activation of Antitumor Resistance Mechanisms and Functional Analogs in Categories of Synergetics].

[Mechanism of Formation of Cardiac Arrhythmia Due to Pathological Distribution of Myocardium Conductivity].

Slurry redox couple thermogalvanic cells with self-sustained stratification and self-replenishment characteristics for efficient body heat harvesting.

High-Entropy Perovskites for Solid Oxide Cells: Mechanistic Insights to Practical Applications.

Interface Issues and Optimization Strategies for Non-Lithium-Metal Anodes in All-Solid-State Batteries.

III-Nitride Nanowire-Based Gas Sensors: From Material Design to Low-Temperature Sensing Performance.

Low-Temperature-Induced Interfacial Transformation of the Aluminum Anode in Alkaline Electrolyte.

Interface engineering-triggered electronic regulation of ReS2 and FeS2 nanosheet arrays for high-performance electrochemical hydrogen evolution.

Related Experiment Videos

[Synthetic Ca++-dependent proton carrier]

Abstract:

Related Concept Videos

Related Articles