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Updated: Feb 7, 2026
06:54
MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
11.8K
Imaging modalities in synchronous oligometastatic prostate cancer
Jurgen J Futterer1, Cristian Surcel2, Roderick van den Bergh3
1Department of Radiology and Nuclear Medicine, Radboudumc, P.O. Box 9101, internal postal code 766, 6500 HB, Nijmegen, The Netherlands. jurgen.futterer@radboudumc.nl.
World Journal of Urology
|August 3, 2018
Summary
Functional imaging, such as 68Ga PSMA PET-CT, effectively detects low-burden metastatic prostate cancer. This aids in identifying patients who may benefit from targeted treatments over systemic therapy.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Oligometastatic prostate cancer is a recently defined subtype characterized by a limited metastatic load.
- This classification suggests a potentially more favorable prognosis and the possibility of curative treatment.
- A knowledge gap exists regarding optimal imaging modalities for classifying this tumor subtype.
Purpose of the Study:
- To investigate the role of conventional and marker-based imaging in synchronous oligometastatic prostate cancer.
- To summarize existing evidence on the clinical application of these imaging techniques.
Main Methods:
- A literature search was conducted on the Pubmed database on December 15th, 2017.
Main Results:
- Functional imaging techniques, particularly 68Ga PSMA PET-CT, demonstrate superior detection rates for nodal, bone, and visceral metastases.
- These methods are especially effective for identifying small lesions in patients with low prostate-specific antigen (PSA) levels.
Conclusions:
- Functional imaging aids in detecting patients with low-burden metastatic disease.
- Limited availability of these modalities may lead to systemic treatment over potentially curative cytoreductive options.
- Ongoing prospective trials aim to guide personalized management for synchronous metastatic patients.
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