Marek's disease--a model for herpesvirus oncology
Related Experiment Video
Updated: Oct 7, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
Abstract:
The article will review the salient features of pathogenesis of Marek's disease in terms of sequential events which occur from the time of virus entry to the development of frank lymphomas. A hypothesis will be presented which will offer a credible explanation for this specific sequence of changes. Then, various factors which influence the incidence of neoplasms will be identified and the possible mechanisms by which they are influential will be discussed. These include the variable oncogenic properties of different virus strains, the influence of host genotype, and immune responses.
Related Concept Videos
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Herpes

