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A cis,fac-[RuCl2(DMSO)3(H2O)] complex exhibits ultrafast photochemical aquation/rearrangement
Svetlana G Matveeva1, Anton A Shushakov, Ivan P Pozdnyakov
1Voevodsky Institute of Chemical Kinetics and Combustion, 3 Institutskaya Str., 630090, Novosibirsk, Russian Federation. svetamat91@gmail.com.
Abstract:
It is known that both cis,fac-[RuCl2(DMSO)3(H2O)] (1a) and trans,cis,cis-[RuCl2(DMSO)2(H2O)2] (2a) complexes, which are formed on the dissolution of trans and cis-isomers of [RuCl2(DMSO)4] in water, demonstrate light-induced anticancer activity. The first stage of 1a photochemistry is its transformation to 2a occurring with a rather high quantum yield, 0.64 ± 0.17. The mechanism of the 1a → 2a phototransformation was studied by means of nanosecond laser flash photolysis and ultrafast pump-probe spectroscopy. The reaction occurs in the picosecond time range via the formation and decay of two successive intermediates interpreted as Ru(ii) complexes with different sets of ligands. A tentative mechanism of phototransformation is proposed.
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