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Updated: Feb 7, 2026

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Fluorescence Recovery after Photobleaching of Yellow Fluorescent Protein Tagged p62 in Aggresome-like Induced Structures
Published on: March 26, 2019
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Publisher Correction: p62 - a new metabolic tumour suppressor
1Nature Reviews Endocrinology, . nrendo@nature.com.
Nature Reviews. Endocrinology
|August 4, 2018
Summary
Adipocyte p62/SQSTM1 plays a crucial role in cancer by regulating metabolism in both adipose tissue and tumors. This protein
Area of Science:
- Molecular Biology
- Oncology
- Metabolism
Context:
- Adipose tissue and tumor microenvironments are critical in cancer progression.
- The protein p62/SQSTM1 (also known as SQSTM1) is implicated in various cellular processes.
Purpose:
- To investigate the role of adipocyte p62/SQSTM1 in tumorigenesis.
- To elucidate the mechanisms by which p62/SQSTM1 regulates metabolism in adipose tissue and tumors.
Summary:
- Adipocyte p62/SQSTM1 suppresses tumor formation by differentially regulating metabolism in adipose tissue and the tumor itself.
- Corrected reference: Huang, J. et al. Cancer Cell 33, 770-784.
Impact:
- Provides insights into the complex interplay between adipose tissue, metabolism, and cancer.
- Highlights p62/SQSTM1 as a potential therapeutic target in cancer.
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