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Iron deficiency in chronic heart failure: case-based practical guidance

Carolyn S P Lam1,2, Wolfram Doehner3, Josep Comin-Colet4,5

  • 1National Heart Centre Singapore, Duke-NUS Medical School, Singapore.

ESC Heart Failure
|August 4, 2018
PubMed

Insights

Iron deficiency in chronic heart failure patients worsens disease and impacts quality of life. This guide offers practical strategies for timely diagnosis and treatment of iron deficiency, even without anemia.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Nutritional Science

Background:

  • Iron deficiency (ID) is a common comorbidity in chronic heart failure (CHF) patients, negatively impacting disease progression and quality of life.
  • Even without concurrent anemia, ID can exacerbate CHF symptoms and outcomes.
  • Current European Society of Cardiology guidelines recommend ID screening and consider intravenous iron therapy for CHF patients.

Purpose of the Study:

  • To provide practical guidance for the diagnosis and management of iron deficiency in patients with chronic heart failure.
  • To address the gap between guideline recommendations and clinical practice regarding iron deficiency treatment in CHF.
  • To improve the routine management of iron deficiency in this patient population.

Main Methods:

  • Review of current European Society of Cardiology guidelines on heart failure diagnosis and treatment.
  • Analysis of the clinical implications of iron deficiency in chronic heart failure.
  • Development of practical diagnostic and therapeutic recommendations, supported by a case study.

Main Results:

  • Iron deficiency is frequently overlooked and undertreated in chronic heart failure patients despite guideline recommendations.
  • Intravenous iron therapy, specifically ferric carboxymaltose, is recommended for treating iron deficiency in CHF.
  • Practical guidance and a case study are provided to aid physicians in managing iron deficiency.

Conclusions:

  • Timely diagnosis and effective management of iron deficiency are crucial for improving outcomes in chronic heart failure patients.
  • Addressing the lack of clinical context is essential for implementing guideline recommendations.
  • This practical guide aims to enhance the routine care of iron deficiency in chronic heart failure.

Keywords:
Case studyChronic heart failureFerric carboxymaltoseIron deficiencyPractical guidance

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