Related Experiment Video
Updated: Feb 7, 2026

10:08
Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
14.0K
Iron deficiency in chronic heart failure: case-based practical guidance
Carolyn S P Lam1,2, Wolfram Doehner3, Josep Comin-Colet4,5
1National Heart Centre Singapore, Duke-NUS Medical School, Singapore.
ESC Heart Failure
|August 4, 2018
Summary
Iron deficiency in chronic heart failure patients worsens disease and impacts quality of life. This guide offers practical strategies for timely diagnosis and treatment of iron deficiency, even without anemia.
Area of Science:
- Cardiology
- Internal Medicine
- Nutritional Science
Background:
- Iron deficiency (ID) is a common comorbidity in chronic heart failure (CHF) patients, negatively impacting disease progression and quality of life.
- Even without concurrent anemia, ID can exacerbate CHF symptoms and outcomes.
- Current European Society of Cardiology guidelines recommend ID screening and consider intravenous iron therapy for CHF patients.
Purpose of the Study:
- To provide practical guidance for the diagnosis and management of iron deficiency in patients with chronic heart failure.
- To address the gap between guideline recommendations and clinical practice regarding iron deficiency treatment in CHF.
- To improve the routine management of iron deficiency in this patient population.
Main Methods:
- Review of current European Society of Cardiology guidelines on heart failure diagnosis and treatment.
- Analysis of the clinical implications of iron deficiency in chronic heart failure.
- Development of practical diagnostic and therapeutic recommendations, supported by a case study.
Main Results:
- Iron deficiency is frequently overlooked and undertreated in chronic heart failure patients despite guideline recommendations.
- Intravenous iron therapy, specifically ferric carboxymaltose, is recommended for treating iron deficiency in CHF.
- Practical guidance and a case study are provided to aid physicians in managing iron deficiency.
Conclusions:
- Timely diagnosis and effective management of iron deficiency are crucial for improving outcomes in chronic heart failure patients.
- Addressing the lack of clinical context is essential for implementing guideline recommendations.
- This practical guide aims to enhance the routine care of iron deficiency in chronic heart failure.
More Related Videos
Related Concept Videos
Heart Failure II: Pathophysiology
964
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
964
Pathophysiology of Heart Failure
3.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.8K
Heart Failure I: Introduction
903
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
903
Heart Failure VI: Adjunct Therapies
348
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
348
Heart Failure Drugs: Diuretics
987
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
987
Heart Failure V: Medical Management
330
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
330

