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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Stroke Prevention in Atrial Fibrillation: Focus on Asian Patients

Yan Guang Li1,2, So Ryoung Lee3, Eue Keun Choi4

  • 1Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom.

Korean Circulation Journal
|August 4, 2018
PubMed

Insights

Atrial fibrillation (AF) increases stroke risk, especially in Asians. This review highlights suboptimal oral anticoagulation use for stroke prevention in Asia despite its proven benefits.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Atrial fibrillation (AF) is a common arrhythmia, significantly increasing stroke risk.
  • Asians face higher AF-related stroke and bleeding risks compared to non-Asians.
  • Effective oral anticoagulation for stroke prevention in AF is well-established but underutilized in Asian populations.

Purpose of the Study:

  • To review evidence on stroke prevention in Asian patients with AF.
  • To evaluate stroke and bleeding risk assessment in this demographic.
  • To summarize the performance and current utilization of oral anticoagulation and thromboprophylaxis in Asia.

Main Methods:

  • Narrative review of existing literature.
  • Focus on studies concerning stroke and bleeding risks in Asian AF patients.
  • Analysis of oral anticoagulation efficacy and real-world usage patterns.

Main Results:

  • Suboptimal use of oral anticoagulation for stroke prevention in Asian AF patients is prevalent.
  • Evidence supports the efficacy and safety of anticoagulation in this population.
  • Gaps exist in risk evaluation and appropriate thromboprophylaxis application.

Conclusions:

  • Improving oral anticoagulation use is critical for stroke prevention in Asian AF patients.
  • Tailored strategies are needed to address underutilization.
  • Further research on risk stratification and management is warranted for the Asian region.

Keywords:
Anticoagulant agentsAsian continental ancestry groupAtrial fibrillationPreventionStroke

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