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Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production
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A new wrinkle: Umbilical cord management (how, when, who)

Anup Katheria1, Shigeharu Hosono2, Walid El-Naggar3

  • 1Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA; Loma Linda Medical University, San Diego, CA, USA.

Seminars in Fetal & Neonatal Medicine
|August 5, 2018
PubMed

In the past five years, umbilical cord management in both term and preterm infants has come full circle, going from the vast majority of infants receiving immediate cord clamping to virtually all governing organizations promoting placental transfusion, mainly in the form of delayed cord clamping (DCC). Placental transfusion refers to the transfer of more blood components to the infant during the first few minutes after birth. The different strategies for ensuring placental transfusion to the baby include delayed (deferred) cord clamping, milking of the attached cord before clamping, and milking of the cut cord. In this review, we address the current evidence to date for providing placental transfusion in different circumstances and the methods for implementation. We also highlight the gaps in knowledge and areas for future research.

Keywords:
Cord bloodDelayed cord clampingImmediate cord clampingPhysiologic-based cord clampingPlacental transfusionUmbilical cord managementUmbilical cord milking

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