Related Experiment Video
Updated: Feb 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Catheter ablation of persistent atrial fibrillation : Possibilities of dipole density mapping]
Christian Meyer1,2, Stephan Willems3,4
1Klinik für Kardiologie mit Schwerpunkt Elektrophysiologie, Universitäres Herzzentrum Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland. Chr.Meyer@uke.de.
Abstract:
Voltage-based methods currently form the diagnostic and therapeutic basis of clinical cardiac electrophysiology. These include both noncontact-based approaches (e.g., body surface electrocardiogram) and established, contact-based 3D mapping systems. At the physiological level, voltage is the measure of an electric field that includes both the local and the sum of the surrounding activation sources. As a result, details of complex rhythm patterns like those observed in atrial fibrillation may be obscured. Dipole density mapping represents an alternative approach to detect and visualize the electrical activity of the heart. It records the local activity on the inner surface of a chamber with high spatial and temporal resolution without requiring contact. This could help to further improve our understanding of the mechanisms and therapeutic possibilities. Herein, we review current knowledge of this procedure, potential uses, and clinical experience to date.
Related Concept Videos
Electric Dipoles and Dipole Moment
Theoretically, studying electric dipoles leads to understanding why the resultant electric forces around us are weak. Since electric forces are strong, remnant net charges are rare. Hence, the interaction between dipoles helps us understand electrical interactions in...
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid Fibrils
Bond Polarity, Dipole Moment, and Percent Ionic Character
Induced Electric Dipoles
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
Fibril-associated Collagen
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...

