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Updated: Feb 7, 2026

Measuring Influenza Neutralizing Antibody Responses to AH3N2 Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells
Published on: November 22, 2017
Preparing for the 2018-2019 influenza season
Annabelle de St Maurice1, Natasha Halasa2
1Department of Pediatrics, Division of Pediatric Infectious Diseases, UCLA David Geffen School of Medicine, Los Angeles, CA.
Abstract:
The 2017-18 influenza season brought record numbers of cases in both the Northern and Southern hemispheres, resulting in high rates of influenza-related hospital admission and death. Estimated efficacy of flu vaccine was low against the most common circulating strain, influenza A (H3N2). Decreased efficacy may be due to changes in circulating virus or mutations that occur in the vaccine strain during the manufacturing process.
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