A compliant aortic model for in vitro simulations: Design and manufacturing process

Area of Science:

• Biomedical Engineering
• Materials Science

Background:

• Existing human aorta models lack realistic mechanical compliance.
• Accurate compliance is crucial for in vitro testing of vascular devices.

Purpose of the Study:

• To design and manufacture a silicone aorta model with accurate geometrical and mechanical properties.
• To develop a compliant tool for in vitro testing of devices interfacing with the vascular system.

Main Methods:

• Parametric design based on literature data.
• Manufacturing using a specific silicone mixture via rapid prototyping and molding.
• Computed tomography scans for mechanical property evaluation.

Main Results:

• High adherence between imposed and measured compliance values across aortic sections.
• Successful validation of the silicone model's mechanical behavior.

Conclusions:

• The developed approach is feasible for creating accurate, compliant aorta models.
• This model can significantly enhance in vitro studies of the vascular system.