Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer02:18

Cancer

54.4K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.4K
What is Cancer?02:12

What is Cancer?

14.5K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.5K
Cancer Prevention02:59

Cancer Prevention

8.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.1K
Cancer Therapies02:49

Cancer Therapies

10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
Cancer Vaccines01:30

Cancer Vaccines

1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K
Skin Cancer01:30

Skin Cancer

5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ANA fluorescence patterns and low C4 are associated with higher antiphospholipid antibody serological intensity in routine diagnostic testing.

Clinical chemistry and laboratory medicine·2026
Same author

Lupus Anticoagulant and Complement C4 Consumption in Antiphospholipid Antibody Testing: Disentangling Inflammation From Autoimmunity.

International journal of laboratory hematology·2026
Same author

Effects on plasma oxytocin and dopamine levels through a five-minute audiovisual stimulus of Greek Syrtaki: An intervention-control primary care study.

Explore (New York, N.Y.)·2025
Same author

Evaluation of the Diagnostic and Predictive Significance of Postoperative C-Reactive Protein to Transferrin or Albumin Ratio in Identifying Septic Events Following Major Abdominal Surgery.

Journal of clinical medicine·2025
Same author

The Sequence [RRKLPVGRS] Is a Nuclear Localization Signal for Importin 8 Binding (NLS8): A Chemical Biology and Bioinformatics Study.

International journal of molecular sciences·2025
Same author

Nuclear translocation of the membrane oxoeicosanoid/androgen receptor, OXER1: Possible mechanisms involved.

Molecular and cellular endocrinology·2024

Related Experiment Video

Updated: Feb 7, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K

Eicosanoids in prostate cancer.

Athanassios A Panagiotopoulos1, Konstantina Kalyvianaki1, Elias Castanas1

  • 1Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, GR-71500, Heraklion, Greece.

Cancer Metastasis Reviews
|August 6, 2018
PubMed
Summary

Dietary polyunsaturated fatty acids and their eicosanoid metabolites are linked to prostate cancer. This review explores the biological activities of lipids, focusing on eicosanoids in prostate cancer development.

Keywords:
5-oxo-eicosatetraenoic acid (5-oxo-ETE)Arachidonic acidHydroxyeicosatetraenoic acids (HETEs)LipoxygenasesPolyunsaturated fatty acids (PUFAs)Prostaglandins

More Related Videos

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

35.9K
miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

11.2K

Related Experiment Videos

Last Updated: Feb 7, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K
An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

35.9K
miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

11.2K

Area of Science:

  • Lipid metabolism and cancer biology.
  • Nutritional epidemiology and oncology.

Background:

  • Epidemiological studies suggest a link between dietary fatty acids and prostate cancer risk.
  • Polyunsaturated fatty acids (PUFAs), including linoleic and alpha-linolenic acid, are common in diets.
  • PUFAs are precursors to eicosanoids, signaling molecules with diverse biological functions.

Purpose of the Study:

  • To review the biological activities of lipids, with a specific focus on eicosanoids.
  • To elucidate the role of eicosanoids in the context of prostate cancer.

Main Methods:

  • Literature review of epidemiological and molecular studies.
  • Analysis of lipid metabolism pathways relevant to eicosanoid production.
  • Synthesis of current knowledge on eicosanoids and prostate cancer.

Main Results:

  • Eicosanoids derived from PUFAs play significant roles in various biological processes.
  • Specific eicosanoids have been implicated in the pathogenesis and progression of prostate cancer.
  • Cellular enzymes like lipoxygenases and cycloxygenases mediate the production of these critical molecules.

Conclusions:

  • Lipid metabolism, particularly eicosanoid pathways, represents a key area for understanding prostate cancer.
  • Further research into eicosanoid signaling could reveal novel therapeutic targets for prostate cancer.