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Updated: Feb 7, 2026

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
Published on: September 8, 2017
[Integrated podiatrist care for prostate cancer patients treated with docetaxel: Feasibility and results]
Hedi Chabanol1, Olivier Huillard1, Lucie Prin1
1AP-HP, hôpital Cochin Port-Royal, service de cancérologie, 123, boulevard Port-Royal, 75014 Paris, France.
Background:
Docetaxel is frequently used for the treatment of metastatic prostate cancer patients. Nail toxicity is a commonly described side effect, but no precise recommendation exists concerning its management. We experimented the integration of a podiatrist in routine cancer care.
Methods:
Patients having received docetaxel for a metastatic prostate cancer since the arrival of the podiatrist were studied.
Results:
Fifty-six patients were included, half had docetaxel-induced nail toxicity and 18 were referred to the podiatrist. The integration of the podiatrist in routine care was feasible and allowed characterizing nail toxicity. The main lesions observed were non-coagulated nail hematomas, coagulated nail hematomas and onycholysis. This experience led to propose an integrated care for docetaxel-induced nail toxicity.
Conclusion:
The integration of podiatrist care is feasible in routine cancer care and can help improving the management of docetaxel-induced nail toxicity in metastatic prostate cancer patients.
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