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Updated: Feb 7, 2026

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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
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Urinothorax Caused by Xanthogranulomatous Pyelonephritis
Waiel Abusnina1, Hazim Bukamur2, Zeynep Koc3
1Department of Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia 25701, USA.
Case Reports in Pulmonology
|August 7, 2018
Summary
Xanthogranulomatous pyelonephritis, a rare kidney infection, can lead to serious complications. This case highlights its rare association with urinothorax, successfully treated with robotic surgery.
Area of Science:
- Nephrology
- Urology
- Pathology
Background:
- Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic kidney infection.
- It typically affects middle-aged women with recurrent urinary tract infections.
- Pathogenesis involves obstructive uropathy, with renal parenchyma replaced by lipid-laden macrophages.
Observation:
- XGP often presents as an enlarged, nonfunctioning kidney.
- Complications include abscess and fistula formation.
- This report details the first case of XGP complicated by urinothorax.
Findings:
- The patient presented with XGP and associated urinothorax.
- Robot-assisted nephrectomy was performed for treatment.
- Resolution of urinothorax was confirmed post-surgery.
Implications:
- This case expands the known complications of XGP.
- It demonstrates the efficacy of robot-assisted nephrectomy in managing complex XGP cases.
- Highlights the importance of considering urinothorax in XGP patients with respiratory symptoms.
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