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Updated: Feb 7, 2026

Author Spotlight: RNA FISH for Locating lncRNA-SNHG6 in Osteosarcoma Cells
Published on: June 16, 2023
Emerging roles of non-coding RNAs in the pathogenesis, diagnosis and prognosis of osteosarcoma
Chongchong Wang1, Juehua Jing2, Li Cheng3
1Department of Oncology, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Abstract:
Non-coding RNAs (ncRNAs) have been found to play essential roles in various physiological and pathological processes. The involvement of ncRNAs in the development of osteosarcoma (OS) has been explored in recent years. In this review, we summarize the functions and mechanisms of microRNA, lncRNA and circRNA in the initiation and progression of OS. We specifically focused on their potential application in the diagnosis, prognosis and therapy of OS. This summary of current knowledge on the involvement of ncRNAs in OS will not only aid comprehension of the complex processes of OS initiation and progression but also contribute to the exploration of ideal diagnostic biomarkers and therapeutic targets for OS patients.
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