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[Comparative Study Of Coronary Artery Disease In Diabetics And Non-Diabetics In The Department Of Cardiology Of
Insights
Diabetic patients with coronary artery disease often experience silent ischemia and multi-vessel disease, requiring more bypass grafting surgery compared to non-diabetics.
Area of Science:
- Cardiology
- Diabetology
- Vascular Medicine
Context:
- Coronary artery disease (CAD) presents differently in diabetic versus non-diabetic populations.
- Understanding these differences is crucial for effective patient management and treatment strategies.
Purpose:
- To compare the clinical features and angiographic findings of coronary artery disease in diabetic and non-diabetic patients.
- To identify specific patterns of CAD presentation and treatment indications in individuals with diabetes.
Summary:
- A case-control study included 45 diabetic and 45 non-diabetic patients undergoing coronary angiography/angioplasty.
- Diabetic patients showed a higher prevalence of silent ischemia (48.9%) and triple-vessel disease (26.7%) compared to non-diabetics.
- Coronary artery bypass grafting was more frequently indicated in diabetic patients (9 vs. 3).
Impact:
- This study highlights the distinct manifestations of CAD in diabetic individuals, emphasizing silent ischemia and multi-vessel involvement.
- Findings suggest a need for tailored diagnostic and therapeutic approaches for diabetic patients with coronary artery disease.
Abstract:
The aim of this study was to compare the features of coronary artery disease between diabetic and non-diabetic patients.
Patients And Methods:
A case-control study was carried out from 1 May 2013 to 31 July 2015 in the department of cardiology of Aristide le Dantec university hospital. Forty-five diabetic patients and forty-five non-diabetic patients who underwent coronary angiography and / or angioplasty were included.
Results:
There was a male predominance with a sex ratio of 1.6 in both groups. The mean age was 62.26 years for diabetics and 59.06 years for non-diabetics (p = 0.6). In diabetics, symptomatology was dominated by silent ischemia (48.9%) versus typical angina pain (68.9%) in non-diabetics. Myocardial infarction was the most common indication of coronary angiography in both groups. Coronary angiography revealed one-vessel disease (46.6% versus 41.7% p = 0.822), double vessel disease (26.7% versus 41.7% p = 0.091) and triple vessel disease (26.7% versus 16.6% p = 0.561). Angioplasty was indicated in 37.8% of diabetics versus 63.9% of non-diabetics. Nine diabetic patients and three non-diabetic patients had an indication of coronary artery bypass grafting.
Conclusion:
Our study confirms the greater frequency of silent ischemia and multiple-vessel disease in diabetics as well as a more frequent indication of coronary artery bypass grafting in these patients.
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