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Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
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Updated: Feb 7, 2026

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
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Methodological approach for trace and essential elements assessment in prostate tissue by SRIXE method.

Bohdan Pawlicki1, Aleksandra Pawlicka, Agnieszka Banas

  • 1Gabriel Narutowicz Hospital, Kraków, Poland. bpawlicki@poczta.onet.pl.

Folia Medica Cracoviensia
|August 7, 2018
PubMed
Summary

Synchrotron Induced X-ray Emission (SRIXE) effectively measures trace and essential elements in prostate tissue. This technique offers high spatial resolution for analyzing elemental changes in disease progression.

Keywords:
Adenocarcinoma prostataeSIXEX‐ray Fluorescenceelemental analysisprostatetrace elements

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Area of Science:

  • Biomedical science
  • Analytical chemistry
  • Pathology

Background:

  • Histopathological analysis focuses on morphology, missing biochemical insights.
  • Assessing elemental composition in tissues is crucial for understanding disease.

Purpose of the Study:

  • Introduce and validate Synchrotron Induced X-ray Emission (SRIXE) for elemental analysis in prostate tissue sections.
  • Familiarize the medical community with this advanced analytical method.

Main Methods:

  • SRIXE technique applied to prostate tissue samples from patients with Adenocarcinoma prostatae.
  • Specimens were freeze-dried, sectioned to 15 μm, and analyzed using SRIXE.

Main Results:

  • SRIXE demonstrated usability for evaluating trace and essential element concentrations.
  • Achieved spatial resolution better than 15 microns for elemental mapping.

Conclusions:

  • SRIXE provides cellular-level elemental analysis without labeling, complementing histopathology.
  • Elemental concentration changes can be correlated with disease progression.
  • The method is applicable to various biological tissues.