[Chemical Constituents from Oldenlandia diffusa]

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Pharmacognosy

Background:

• Oldenlandia diffusa is a traditional medicinal herb.
• Understanding its chemical composition is crucial for its medicinal applications.

Purpose of the Study:

• To identify and characterize the chemical constituents present in the water extract of Oldenlandia diffusa.

Main Methods:

• Compounds were isolated using various chromatographic techniques including column chromatography and HPLC.
• Structures were determined through physicochemical analysis and spectral data interpretation.

Main Results:

• Sixteen compounds were successfully isolated and identified.
• These include asperuloside, deacetyl asperuloside, geniposide, 10-dehydrogeniposide, daphylloside, diffusoside A, diffusoside B, coniferin, scandoside methyl ester, acetyl scandoside methyl ester, deacetylasperulosidic acid methyl ester, gardenoside, galioside, galioside 10-acetate, loliolide, and (+)-neo-olivil.

Conclusions:

• The study successfully elucidated the chemical profile of the Oldenlandia diffusa water extract.
• Geniposide, coniferin, galioside 10-acetate, and (+)-neo-olivil were reported from this plant for the first time, expanding the knowledge of its constituents.