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Updated: Feb 7, 2026

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
Unsuspected Metastases to Muscles in Osteosarcoma Detected on 18F-Sodium Fluoride PET-CT
Sharjeel Usmani, Fahad Marafi1, Rashid Rasheed
1Jaber Al-Ahmad Molecular Imaging Center.
Abstract:
Metastasis of osteosarcoma to the muscles is extremely rare. F-sodium fluoride (NaF) is a bone-seeking agent that can also localize extraosseous calcifying lesions. We report the case of a 33-year-old woman with osteosarcoma of the right fibula treated with surgery and chemotherapy 2 years back who was referred for F-NaF PET-CT to evaluate possible metastatic lesions. F-NaF PET-CT unexpectedly detected 2 foci of soft tissue increased tracer uptake in the right lateral abdominal and left paraspinal muscles, which corresponded to the focal calcification in the muscles. The pathological examination revealed metastatic osteosarcoma to the muscles.
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