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An Update on Sexual Transmission of Zika Virus

Hercules Sakkas1, Petros Bozidis2, Xenofon Giannakopoulos3

  • 1Microbiology Department, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece. isakkas@uoi.gr.

Pathogens (Basel, Switzerland)
|August 8, 2018
PubMed

Insights

Zika virus (ZIKV), primarily mosquito-borne, can cause neuroimmunological disorders. Emerging evidence shows ZIKV also transmits sexually, impacting the male reproductive system.

Area of Science:

  • Virology
  • Neuroimmunology
  • Epidemiology

Background:

  • Zika virus (ZIKV) is an arbovirus transmitted by Aedes mosquitoes.
  • ZIKV infections are typically asymptomatic or mild but linked to neurological issues like Guillain-Barré syndrome and microcephaly.
  • Sexual transmission of ZIKV is a recent, significant finding, unlike other flaviviruses.

Purpose of the Study:

  • To review current knowledge on Zika virus.
  • To focus on the sexual transmission of ZIKV.
  • To examine ZIKV's effects on the male reproductive system.

Main Methods:

  • Literature review of recent studies on ZIKV.
  • Analysis of epidemiological data on ZIKV transmission.
  • Synthesis of findings on ZIKV's impact on male reproduction.

Main Results:

  • ZIKV exhibits sexual transmission, a novel characteristic for mosquito-borne flaviviruses.
  • ZIKV infection has demonstrable consequences for the male reproductive system.
  • Epidemiological data confirm human-to-human sexual transmission of ZIKV.

Conclusions:

  • Zika virus poses a dual threat via mosquito and sexual transmission.
  • Understanding ZIKV's reproductive effects is crucial for public health.
  • Further research is needed on ZIKV's long-term reproductive health impacts.
Keywords:
AedesHost-virus interactionsZika virusepidemicsflavivirussexual transmissiontestis

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