Magnetic frame work composite as an efficient sorbent for magnetic solid-phase extraction of plasticizer compounds

Area of Science:

• Materials Science: Fabrication and characterization of novel metal-organic frameworks (MOFs).
• Analytical Chemistry: Development of advanced solid-phase extraction techniques.

Background:

• Plasticizers are common environmental contaminants.
• Accurate detection of plasticizers is crucial for environmental and health monitoring.
• Existing analytical methods require efficient preconcentration steps.

Purpose of the Study:

• To synthesize and evaluate two amide-functionalized MOFs, TMU-23 and TMU-24, for magnetic solid-phase extraction (MSPE) of plasticizers.
• To develop a sensitive method for determining plasticizers using GC-FID.
• To optimize the MSPE process using the most effective MOF.

Main Methods:

• Synthesis of TMU-23 and TMU-24 MOFs with amide-functionalized pores.
• Fabrication of magnetic TMU-24 via in-situ synthesis of a magnetic core-shell nanocomposite.
• Application of magnetic TMU-24 as a sorbent for MSPE of benzylbutylphthalate (BBP), di-2-(ethylhexyl) phthalate (DEHP), and di-n-butyl phthalate (DBP).
• Analysis of extracted analytes using gas chromatography with flame ionization detection (GC-FID).

Main Results:

• TMU-24 exhibited superior adsorption capabilities compared to TMU-23 due to its surface area, porous structure, and interaction potential.
• Optimized MSPE with magnetic TMU-24 achieved high preconcentration factors (189-278) and recoveries (92.0-102.0%).
• The method demonstrated good linearity (R² > 0.99), low limits of detection (0.2-0.4 μg L⁻¹), and acceptable precision (RSD 3.9-5.9%).

Conclusions:

• Amide-functionalized MOFs, particularly magnetic TMU-24, are effective sorbents for MSPE of target plasticizers.
• The developed method offers a sensitive, efficient, and reliable approach for plasticizer determination in samples.
• This work highlights the potential of MOFs in environmental analysis and contaminant monitoring.