Propolis: Chemical Composition and Its Applications in Endodontics

Area of Science:

• Biochemistry
• Dental Science
• Natural Products Chemistry

Background:

• Propolis is a resinous mixture produced by honey bees.
• Its chemical composition varies based on geographic origin and botanical sources.
• Propolis possesses a wide range of biological activities.

Purpose of the Study:

• To review the chemical composition of propolis.
• To explore the applications of propolis in endodontics.

Main Methods:

• Literature search conducted on ScienceDirect, PubMed, and World of Chemicals.
• Included studies published from 1988 to February 2018.

Main Results:

• Flavonoids are key compounds in propolis, exhibiting anti-inflammatory, anti-viral, anti-allergic, anti-cancer, anti-bacterial, and antioxidant effects.
• Propolis can be utilized as an endodontic irrigation solution and intracanal medicament.
• It maintains periodontal ligament cell vitality, inhibits osteoclastic activity, induces tubular dentin formation, and reduces pulp inflammation.

Conclusions:

• Propolis, containing resin, pollen, vitamins, flavonoids, and phenols, has diverse endodontic applications.
• It holds significant promise for future advancements in both medicine and dentistry.