Defining a mood stabiliser: novel framework for research and clinical practice
Gin S Malhi1, Richard Porter2, Lauren Irwin1
1Treatment Algorithm Group (TAG), Academic Department of Psychiatry, Northern Sydney Local Health District, Sydney Medical School Northern, University of Sydney, Australia and CADE Clinic, Royal North Shore Hospital, Northern Sydney Local Health District, Australia.
Bjpsych Open
|August 8, 2018
Summary
The term "mood stabilizer" is poorly defined. This study proposes a standardized framework to evaluate and communicate the efficacy of medications for mania and depression, improving clinical practice.
Area of Science:
- Psychiatry
- Pharmacology
Background:
- The term 'mood stabilizer' is ill-defined and lacks clinical utility.
- The Treatment Algorithm Group (TAG) developed this framework with logistical support from Servier.
Purpose of the Study:
- To propose a standardized framework for evaluating mood-stabilizing medications.
- To improve communication regarding medication efficacy in mania and depression.
Main Methods:
- Development of a standardized framework to assess mood-stabilizing properties.
- Evaluation of acute and prophylactic efficacy across mania and depression domains.
Main Results:
- The proposed framework offers a common definition for mood stabilizers.
- This standardization aims to facilitate research and clinical practice.
Conclusions:
- A standardized framework is needed to define and evaluate mood stabilizers.
- The proposed framework enhances clarity and utility in clinical settings and research.
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