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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
Iodate induced toxic retinopathy: a case report
Y C Venu Gopal Reddy1, Anuj Sharma1, Adheesh P Shetty1
1Aravind Eye Hospital, S.N. High Road, Tirunelveli, Tamil Nadu 627001 India.
Background:
Iodine deficiency is a common preventable cause of intellectual and developmental disabilities. Iodine in the form of potassium iodate is added to the common salt under the National Iodine Deficiency Disorder Control Program in India. Overdose of iodate can lead to retinal toxicity.
Case Presentation:
We hereby present a case of a 34 year old male patient who presented to us 10 years following iodate ingestion. There was widespread outer retinal atrophy, foveal atrophy and sub-retinal fibrosis noted on fundus evaluation. The fundus fluorescein angiogram was suggestive of window defects while the scotopic electroretinogram showed diminished amplitude pointing towards a grave prognosis.
Conclusions:
Excessive ingestion of potassium iodate can lead to outer retinal atrophy due to its toxicity to the retinal pigment epithelium and photo-receptors. The degree of damage is dependent on the ingested dose.
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Types of Reports I: Hands-off Report
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Purpose and Process:
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Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Types of Reports II: Incident or Occurrence Report
Purposes:
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Here's an overview of each type:
Telephone Orders
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