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An overview of meningiomas
Robin A Buerki1, Craig M Horbinski2,3, Timothy Kruser3,4
1Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Ave., San Francisco, CA 94143, USA.
Future Oncology (London, England)
|August 8, 2018
Summary
Meningiomas, common brain tumors, are seeing rapid research advances. These developments promise to significantly improve diagnosis and treatment strategies for meningioma patients in the near future.
Area of Science:
- Neuro-oncology
- Pathology
- Genetics
Background:
- Meningiomas are the most frequent primary tumors within the skull.
- Significant advancements in meningioma research are anticipated to influence clinical management.
- The 2016 World Health Organization (WHO) classification update for central nervous system (CNS) tumors has refined meningioma categorization.
Purpose of the Study:
- To provide a comprehensive review of meningioma pathology, classification, and clinical management.
- To update readers on the latest therapeutic strategies, including surgery, radiotherapy, and emerging systemic/targeted therapies.
- To outline future research directions and potential impacts on meningioma care.
Main Methods:
- Review of current literature on meningioma histo- and molecular pathology.
- Analysis of clinical and radiographic presentations.
- Evaluation of established and investigational therapeutic modalities.
Main Results:
- The review details the updated WHO classification of meningiomas.
- It covers surgical and radiotherapeutic approaches.
- It summarizes data on systemic and targeted therapies.
Conclusions:
- Contemporary meningioma management is evolving rapidly.
- Ongoing research holds promise for improved patient outcomes.
- Future directions emphasize personalized and targeted treatment strategies.
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