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Related Experiment Video

Updated: Feb 6, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
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Steroid Use for Sudden Sensorineural Hearing Loss: A CHEER Network Study.

David L Witsell1, Hillary Mulder2, Steven Rauch3

  • 11 Division of Head and Neck Surgery and Communication Sciences, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|August 8, 2018
PubMed
Summary

Corticosteroid treatment for sudden sensorineural hearing loss showed hearing improvement in most patients, but no significant differences were found between oral and intratympanic delivery methods. Further research is needed to determine optimal treatment strategies.

Keywords:
CHEER Networkpractice guidelinessteroidssudden sensorineural hearing loss

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Area of Science:

  • Otolaryngology
  • Neurology
  • Pharmacology

Background:

  • Sudden sensorineural hearing loss (SSNHL) is a medical emergency requiring prompt treatment.
  • Corticosteroids are a primary treatment modality for SSNHL, but optimal delivery methods remain debated.
  • Understanding treatment patterns and effectiveness is crucial for improving patient outcomes.

Purpose of the Study:

  • To describe patterns of corticosteroid administration for SSNHL.
  • To evaluate the effectiveness of different corticosteroid delivery modes (oral vs. intratympanic vs. both) for SSNHL.
  • To identify potential areas for optimizing SSNHL treatment protocols.

Main Methods:

  • A cross-sectional, repeated measures study design was employed.
  • 117 patients treated for SSNHL within the Creating Healthcare Excellence through Education and Research (CHEER) Network were analyzed.
  • Audiometric scores, speech scores, and patient-perceived improvement were assessed; statistical analyses included Wilcoxon rank-sum and Fisher exact tests.

Main Results:

  • Improvements in audiometric and speech scores were observed in patients treated with corticosteroids.
  • 57% of patients reported subjective hearing improvement.
  • No statistically significant differences in hearing improvement were found between oral and combined oral/intratympanic corticosteroid treatment groups.

Conclusions:

  • While a majority of patients experienced some hearing improvement with steroid treatment, statistical significance was not consistently met.
  • The study's sample size may have limited the ability to detect significant differences between treatment groups.
  • Pragmatic clinical trials and large-scale data analysis are suggested for future best practice development in SSNHL treatment.