Related Experiment Video

Updated: Feb 6, 2026

Imaging G Protein-coupled Receptor-mediated Chemotaxis and its Signaling Events in Neutrophil-like HL60 Cells
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Published on: September 14, 2016

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Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation.

Pilar Esteve1, Inmaculada Crespo1, Polynikis Kaimakis1

  • 1Centro de Biología Molecular "Severo Ochoa", CSIC-UAM and CIBER de Enfermedades Raras (CIBERER), c/Nicolás Cabrera, Madrid, Spain.

Cerebral Cortex (New York, N.Y. : 1991)
|August 8, 2018
PubMed
Summary

Secreted Frizzled Related Protein 1 (Sfrp1) coordinates brain development by balancing Wnt and Notch signaling pathways. Its absence disrupts hippocampal and neocortical patterning, affecting cell proliferation and neuronal generation.

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