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Updated: Feb 6, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Incidence of complications related to catheter ablation of atrial fibrillation and atrial flutter: a nationwide
Gerhard Steinbeck1, Moritz F Sinner2,3, Manuel Lutz4
1University Hospital Munich, Ludwig Maximilians University, Marchioninistr. 15, Munich, Bavaria, Germany.
Catheter ablation for atrial fibrillation and flutter has higher real-world complication rates than previously reported. Low-volume centers and atrial flutter procedures showed increased risks, especially in elderly patients with comorbidities.
Area of Science:
- Cardiology
- Medical Informatics
- Public Health
Background:
- Existing data on catheter ablation risks may underestimate real-world outcomes.
- Nationwide assessment is crucial for understanding actual complication rates.
Purpose of the Study:
- To evaluate the in-hospital complication rates of catheter ablation for atrial fibrillation and atrial flutter in Germany.
- To compare complication rates based on procedure type, energy source, center volume, and patient comorbidities.
Main Methods:
- Analysis of nationwide administrative data from 33,353 in-hospital cases in Germany in 2014.
- Utilized ICD-10-GM and German Operation and Procedure Classification (OPS) codes.
- Stratified analysis by ablation type (left atrial vs. atrial flutter) and center volume.
Main Results:
- Overall complication rates for left atrial ablation: 11.7%-13.8%; major complications: 3.8%-7.2%.
- Atrial flutter ablation had lower overall rates (10.5%) but higher major complication rates (7.4%) and in-hospital deaths (0.34% vs. 0.09%).
- Centers performing >100 left atrial ablations annually had significantly fewer complications (12.7% vs. 16.4%).
Conclusions:
- Nationwide data reveal higher-than-expected complication rates for catheter ablation in Germany.
- Atrial flutter ablations carry a surprisingly high risk of major complications.
- Advanced age and comorbidities significantly influence complication risk; low-volume centers pose a higher risk.
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