Related Experiment Video
Updated: Feb 6, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
COMPARATIVE STUDY OF TWO EXPERIMENTAL MODELS OF CHRONIC ARTHRITIS IN RATS
Abstract:
This work was aimed at comparative analysis of the two experimental models of chronic arthritis induced in rats by the administration of (i) complete Freund's adjuvant (CFA) and (ii) carrageenan. The clinical and histological signs of pathology were assessed using a categorical rating system. It is established that the administration of CFA leads to the development of pathology closely resembling rheumatoid arthritis. In contrast, the administration of c.arrageenan promotes chronic inflammatory arthritis without autoimmune component. The results can serve a basis for selecting a methodological approach to assess the effectiveness of drugs with anti-rheumatoid, anti-inflammatory, and/or immunomodulatory properties.
Related Concept Videos
Comparing Experimental Results: Student's t-Test
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Comparative Excretory Systems
Comparing the Survival Analysis of Two or More Groups
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

