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Updated: Feb 6, 2026

07:59
A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
Published on: March 25, 2014
15.6K
Abstract:
MHC expression may affect response to immune checkpoint inhibitors in patients with advanced melanoma. In a recent retrospective analysis, patients with low MHC class I expression responded to a PD-1 inhibitor, but were less likely to respond to a CTLA4 inhibitor than patients with higher MHC class I expression.
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